A Monte Carlo Estimation of the Narrow-Sense Heritability of COVID-19 Infection and Severity from AncestryDNA Survey Data
Abstract
Respiratory infectious diseases, such as COVID-19, demonstrate a host genetic component that contributes to interindividual differences of susceptibility and infection. At present, the relative effect of environmental and genetic factors of COVID-19 is unknown. This research presents a Monte Carlo (MC) estimation of the genetic narrow-sense heritability of COVID-19 infection and severity from AncestryDNA survey data. The results suggest a moderate genetic contribution to COVID-19 infection and a low genetic contribution for COVID-19 severity.
02 /Specification & Classification
Click any tag to browse matching papers- Citations
- 1
- Organism
- Assay
- Research Focus
- Approach
Reproducibility ledger
Nobody has reported trying to reproduce this paper yet. Did you replicate an experiment or run the code? Your report saves the next lab a week.
Sign in to file a reproducibility report.
Related papers
- Self-reported symptoms of covid-19 including symptoms most predictive of SARS-CoV-2 infection, are heritable
Frances M. K. Williams, Maxim B. Freidin, … Tim D. Spector·Twin Research and Human GeneticsPeer-reviewed·Dec 1, 2020
- On Statistical Power for Case-Control Host Genomic Studies of COVID-19
Yu‐Chung Lin, Jennifer D. Brooks, … Lisa J. Strug·Genome MedicinePeer-reviewed·Dec 1, 2020
- The major genetic risk factor for severe COVID-19 is inherited from Neandertals
Hugo Zeberg, Svante Pääbo·NaturePeer-reviewed·Sep 30, 2020
- A genome-wide association study of COVID-19 related hospitalization in Spain reveals genetic disparities among sexes
Ángel Carracedo·medRxiv·Nov 24, 2021
- Mapping the human genetic architecture of COVID-19 by worldwide meta-analysis
Mari Niemi, Juha M Karjalainen, … Bahareh Sedaghati-khayat·Research at the University of Copenhagen (University of Copenhagen)Peer-reviewed·Jan 1, 2021
- Shared Genomic Architectures of Covid-19 and Antisocial Behavior
Charleen D. Adams, Jorim J. Tielbeek, Brian B. Boutwell·Translational PsychiatryPeer-reviewed·May 10, 2022