SCI-VCF: A cross-platform GUI solution to Summarise, Compare, Inspect, and Visualise the Variant Call Format

Abstract

As genomics advances swiftly and its applications extend to diverse fields, bioinformatics tools must enable researchers and clinicians to work with genomic data irrespective of their programming expertise. We developed SCI-VCF, a Shiny-based comprehensive analysis utility to summarise, compare, inspect, analyse, and design interactive visualisations of the genetic variants from the variant call format. With an intuitive GUI, SCI-VCF aims to bridge the approachability gap in genomics that arises from the existing predominantly command-line utilities. SCI-VCF is written with R and is freely available at https://github.com/HimanshuLab/SCI-VCF. For installation-free access, users can avail of an online version at https://ibse.shinyapps.io/sci-vcf-online/.