bioRxivAnimal Behavior & CognitionPreprint
Molecular fingerprints in the hippocampus of alcohol seeking during withdrawal
R. Pagano, A. Salamian, E. Skonieczna, B. Wojtas, B. Gielniewski, Z. Harda, A. Cały, R. Havekes, T. Abel, K. Radwaska
Abstract
Alcohol use disorder (AUD) is characterized by excessive alcohol seeking and use. Here, we investigated the molecular correlates of impaired extinction of alcohol seeking using a multidimentional mouse model of AUD. We distinguished AUD-prone and AUD-resistant mice, based on the presence of [≥] 2 or View larger version (41K): org.highwire.dtl.DTLVardef@14b3fadorg.highwire.dtl.DTLVardef@141b1fdorg.highwire.dtl.DTLVardef@c82b8org.highwire.dtl.DTLVardef@15a16ad_HPS_FORMAT_FIGEXP M_FIG C_FIG
- organism: mouse
- assay: bulk RNA-seq
- research focus: host-pathogen & immune response
- approach: experimental assay
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