bioRxivBioengineeringPreprint
Optimising digital volume correlation across materials: a practical framework for accuracy and spatial resolution
Alissa Louise ParmenteriD, Aikta SharmaiD, Brian K. BayiD, Peter David LeeiD
Abstract
Digital volume correlation (DVC) provides full-field three-dimensional measurements of internal deformation, but its accuracy and effective spatial resolution depend on image-processing and analysis choices. Here, we use fibrous, cartilaginous and mineralised tissues within a rat intervertebral disc (IVD) as a controlled multi-material case study, combining virtual compression with experimentally loaded synchrotron computed tomography images. We systematically evaluate phase retrieval and image filtering, bit-depth conversion, point-cloud design, subvolume size and strain-field smoothing. Stronger phase retrieval reduced correlation residuals while increasing displacement and strain errors, showing that residual minimisation alone can select poorer parameters. Image filtering sensitivity was greatest in fibrous tissue, which had the smallest characteristic image feature size, whereas inappropriate intensity mapping during 16-bit to 8-bit conversion preferentially degraded low-contrast cartilage. Increasing subvolume size, point spacing or strain-window size improved measurement robustness but progressively smoothed local strain heterogeneity. We demonstrate that the spatial resolution of strain measurement must be matched across tissue types in order to compare strain magnitude; in the IVD, matching DVC spatial resolution changed the apparent ratio of compressive strain among fibrous, cartilaginous and mineralised tissues from 3.1:1.9:1 to 14:7.7:1. These findings establish a sequential, deformation-based optimisation framework in which image characteristics guide processing, known deformations validate accuracy and strain fields are compared at matched measurement scales. The framework supports more reproducible and mechanically interpretable DVC analyses in heterogeneous biological and engineered materials.
- Citations
- 0
Reproducibility ledger
Nobody has reported trying to reproduce this paper yet. Did you replicate an experiment or run the code? Your report saves the next lab a week.
Sign in to file a reproducibility report.
Related papers
- Evaluation of direct strain field prediction in bone with data-driven image mechanics (D2IM-Strain)
Jon Valijonov, Peter Soar, … Gianluca Tozzi·bioRxiv·May 5, 2026
- A high-accuracy and high-efficiency digital volume correlation method to characterize in-vivo optic nerve head biomechanics from optical coherence tomography
F. Zhong, J. Wei, … I. A. Sigal·bioRxiv·Aug 7, 2021
- Data-driven image mechanics (D2IM): a deep learning approach to predict displacement and strain fields from undeformed X-ray tomography images - Evaluation of bone mechanics.
- Multimodal imaging reveals multiscale mechanical interplay in vertebral endplate microarchitecture during intervertebral disc loading
Alissa Louise Parmenter, Elis Newham, … Peter David Lee·Cell BiomaterialsPeer-reviewed·Jul 22, 2025
- Intervertebral Disc Elastography to Relate Shear Modulus and Relaxometry in Compression and Bending
Z. R. Davis, P. C. Gossett, … D. D. Chan·bioRxiv·Sep 1, 2023
- Quantifying Brittle Crack Opening in Human Trabecular Bone Using Synchrotron XCT-DVC
Dhruv Vasooja, A.F. Cinar, … Richard L. Abel·BiomechanicsPeer-reviewed·Jul 3, 2026