Elis Newham

Loss of lmx1ba drives premature osteoarthritis through disruption of skeletal homeostasis

This study shows that loss of lmx1ba in zebrafish causes premature osteoarthritis by disrupting skeletal homeostasis and joint maintenance in adult life.

Synchrotron Tomography-Based Inversion Pipeline for Estimating Elastic Properties of Rat Vertebral Endplate Finite Element Models

This paper develops an inversion pipeline using synchrotron tomography and digital volume correlation to estimate elastic properties of rat vertebral endplates, showing high spatial agreement between FEM predictions and experimental data.

Multimodal X-ray imaging reveals hierarchical fibre mechanics

This paper introduces TomoSAXS to map fibril-to-fibre mechanics in intervertebral discs and shows how pre-strain and strain variability correlate with mechanical behavior.

Multimodal imaging reveals multiscale mechanical interplay in vertebral endplate microarchitecture during intervertebral disc loading

This study uses multimodal imaging to examine mechanical strain and microarchitecture in vertebral endplates during intervertebral disc loading, revealing multiscale structural adaptations.