Alissa Louise Parmenter

Cross-species structure-mechanics prediction in the intervertebral disc

This study develops a cross-species framework linking collagen structure to mechanical vulnerability in intervertebral discs using multiscale imaging and modeling.

Revealing multiscale architecture of the intact human spine using hierarchical phase contrast tomography

This paper uses HiP-CT to image the human spine at high resolution, revealing multiscale anatomy and microstructural features without exogenous contrast.

Articular calcified cartilage microarchitecture has a predictive role in abnormal osteochondral strain distributions in murine age-related osteoarthritis

This study shows that microarchitectural features of articular calcified cartilage in mice predict abnormal strain distributions in osteoarthritis.

Optimising digital volume correlation across materials: a practical framework for accuracy and spatial resolution

This paper optimizes digital volume correlation (DVC) for multi-material biological tissues by evaluating image processing parameters and demonstrating a framework for accurate strain measurement across different tissue types.

Synchrotron Tomography-Based Inversion Pipeline for Estimating Elastic Properties of Rat Vertebral Endplate Finite Element Models

This paper develops an inversion pipeline using synchrotron tomography and digital volume correlation to estimate elastic properties of rat vertebral endplates, showing high spatial agreement between FEM predictions and experimental data.

In situ profiling of nanoscale displacements uncovers mechano-architectural predictors of osteoarthritis emergence

This study uses imaging and modeling to show how structural changes in knee joints predict osteoarthritis onset by altering strain distribution.

Multimodal X-ray imaging reveals hierarchical fibre mechanics

This paper introduces TomoSAXS to map fibril-to-fibre mechanics in intervertebral discs and shows how pre-strain and strain variability correlate with mechanical behavior.

Multimodal imaging reveals multiscale mechanical interplay in vertebral endplate microarchitecture during intervertebral disc loading

This study uses multimodal imaging to examine mechanical strain and microarchitecture in vertebral endplates during intervertebral disc loading, revealing multiscale structural adaptations.