What can astrocytes compute?
Abstract
A foundational result in neural computation was proving the firing-rate model of neurons defines a universal function approximator. In this paper I prove it is possible for astrocytes to compute anything neurons can, by extending this original proof to a model of calcium waves in astrocytes. I confirm this in a series of computer simulations. The major limit for astrocytes, it turns out, is not their ability to learn solutions but the computational complexity of their network. I suggest some initial experiments that might be used to confirm these predictions.
02 /Specification & Classification
Click any tag to browse matching papersReproducibility ledger
Nobody has reported trying to reproduce this paper yet. Did you replicate an experiment or run the code? Your report saves the next lab a week.
Sign in to file a reproducibility report.
Related papers
- Multi-timescale Computation by Astrocytes
- Building Transformers from Neurons and Astrocytes
Leo Kozachkov, Ksenia V. Kastanenka, Dmitry Krotov·Proceedings of the National Academy of SciencesPeer-reviewed·Aug 14, 2023
- Parameter Inference for an Astrocyte Model using Machine Learning Approaches
L. Fritschi, K. Lenk·bioRxiv·May 16, 2023
- Astrocytes encode complex behaviorally relevant information
Katharina Merten, Robert W. Folk, … Axel Nimmerjahn·bioRxiv·Oct 9, 2021
- Astroglial biophysics probed with a realistic cell model
Leonid P. Savtchenko, Lucie Bard, … Dmitri A. Rusakov·bioRxiv·Jun 17, 2018
- Modeling of astrocyte networks: towards realistic topology and dynamics
Вервейко Дарья Вячеславовна, Andrey Yu. Verisokin, … Alexey Brazhe·Frontiers in Cellular NeurosciencePeer-reviewed·Mar 5, 2021