Emerging infectious diseasesMicrobiologyPeer-reviewed journal article
Genomic characterization of a unique population of Leishmania tropica in a new emerging focus of cutaneous leishmaniasis in Somali region of Ethiopia
Adugna AberaiD, Pieter MonsieursiD, Myrthe PareyniD, Dereje Beyene, Geremew TasewiD, Allison Aroni-SotoiD, Mahlet BelachewiD, Dessalegn GeletaiD, Bethlehem AdnewiD, Bokretsion Gidey, Henok Tadesse, Atsbeha Gebreegziabxier, Rajiha Abubeker, Abraham AliiD, Ketema TafessiD, Tobias F. Rinke de WitiD, Johan van GriensveniD, Jean‐Claude DujardiniD, Dawit WoldayiD, Malgorzata A. DomagalskaiD
Abstract
We sequenced Leishmania tropica genomes directly from eight human skin samples collected in a newly emerging focus of cutaneous leishmaniasis in Somali region, Ethiopia. We found a new variant with unique genomic signatures of drug resistance. Genomic homogeneity in the sampled population demonstrates the occurrence of a L. tropica outbreak.
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- top 7%
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