bioRxivMicrobiologyPreprint
Establishing RPTE-derived cell lines expressing hTERT for studying BK polyomavirus
Abstract
We previously established an infection model for BKPyV in primary human renal proximal tubule epithelial (RPTE) cells. Use of these cells is limited by their inability to be passaged extensively. We describe RPTE cells immortalized with hTERT, which can serve as a model system for acute or persistent BKPyV infection.
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