Advanced Radiotherapy Techniques

Dosimetric Characterization and Workflow Optimization of the FLASH-SARRP for Reliable Preclinical Radiobiological Studies

This paper characterizes the FLASH-SARRP irradiator and validates a QA workflow to improve dose reproducibility in preclinical FLASH experiments.

Development of a Multidose Irradiation Protocol for Clonogenic Assays in Cell Culture Plates

The paper develops a multidose irradiation system for cell culture plates to deliver three distinct doses simultaneously, reducing variability and resource use while maintaining radiobiological accuracy.

Genomic-Adjusted Radiation Dose from Bulk RNA Sequencing for Personalized Radiotherapy

This paper develops an RNA sequencing-based radiosensitivity index (RSI-seq) that preserves the clinical utility of the genomic-adjusted radiation dose (GARD) model, enabling personalized radiotherapy across diverse cancer types.

Graded NTCP dynamics: leveraging patient-reported outcomes to explore response and cross-toxicity trade-offs in head and neck cancer

This paper develops a mathematical model of NTCP to capture graded toxicity dynamics in head and neck cancer by integrating tumor response and patient-reported outcomes.

An Investigation of mini-GRID Radiation therapy with Immune Checkpoint Blockade in a Murine Tumor Model

This study evaluates mini-GRID radiotherapy combined with anti-PD-1 in a murine tumor model, finding no improvement in tumor growth delay or survival compared to conventional radiotherapy.

An improved SIFT algorithm based method for detecting of tumor tissue movement in respiratory motion

This paper evaluates SIFT and cross-correlation for detecting tumor tissue movement in respiratory motion using phantoms and finds no significant difference between the methods.

Mitigating Chemotherapy Side Effects through Targeted Gamma-Ray Delivery and Convolutional Neural Networks: A Step Toward Precision Oncology

This paper combines CNNs with gamma-ray delivery to target cancer cells, reducing side effects in synthetic models.