Author

L. L. Kunz

University of GenevaORCID 0009-0008-6526-6025Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:development & morphogenesis· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Marie‐Catherine VozeniniD· 4 shared Benoît PetitiD· 3 shared Charles L. LimoliiD· 3 shared Michèle KnoliD· 3 shared Aymeric AlmeidaiD· 2 shared Jonathan Ollivier· 2 shared Pelagia Pauletta TsoutsouiD· 2 shared Pierre KoryskoiD· 2 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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4 shared papersCancer Biology

Marie‐Catherine VozeninORCID

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4 papers

Recent·Most cited

Cancer BiologybioRxivPreprintNov 1, 2026

✦ In-depth digest

Differential and regionally distinct molecular responses distinguish FLASH and conventional RT in a medulloblastoma model while preserving therapeutic outcomes

Michèle Knol, Javier Franco‐Pérez, Aymeric Almeida…·Paola Ballesteros‐Zebadúa

Hypo-fractionated FLASH and conventional radiotherapy (3x10 Gy) each ablated orthotopic human medulloblastoma in nude mice; FLASH evoked distinct microglial and hippocampal transcriptional programs and less neuroinflammation.

DOI 10.64898/2026.03.16.712103

mousehuman

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Cancer BiologybioRxivPreprintNov 1, 2026

Dosimetric Characterization and Workflow Optimization of the FLASH-SARRP for Reliable Preclinical Radiobiological Studies

Michèle Knol, Patrik Gonçalves Jorge, L. L. Kunz…·Julie Lascaud

This paper characterizes the FLASH-SARRP irradiator and validates a QA workflow to improve dose reproducibility in preclinical FLASH experiments.

DOI 10.64898/2026.07.06.736680

experimental assay

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Cancer BiologybioRxivPreprintMay 19, 2026

Neuroprotection following FLASH-RT may be mediated by sustained glutamate receptor AMPAR activation in CA3 neurons

Louis V. Kunz, Aymeric Almeida, Michèle Knol…·Marie‐Catherine Vozenin

This study investigates FLASH-RT's neuroprotective effects by showing sustained AMPAR activation in CA3 neurons through early transcriptional upregulation of glutamate receptor genes.

DOI 10.64898/2026.05.15.725423

mousebulk RNA-seq

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Cancer BiologyRadiotherapy and OncologyPeer-reviewedMay 20, 2025

Modification of the microstructure of the CERN- CLEAR-VHEE beam at the picosecond scale modifies ZFE morphogenesis but has no impact on hydrogen peroxide production.

Houda Kacem, L. L. Kunz, Pierre Korysko…·Marie‐Catherine Vozenin

This study investigates how modifying the microstructure of a CERN CLEAR-VHEE beam at the picosecond scale affects zebrafish embryo morphogenesis and hydrogen peroxide production.

20 citationstop 1%

zebrafishexperimental assay

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