Author

Michèle Knol

University of GenevaORCID 0009-0005-9688-6110Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Benoît PetitiD· 3 shared Louis V. KunziD· 3 shared Marie‐Catherine VozeniniD· 3 shared Aymeric AlmeidaiD· 2 shared Charles L. LimoliiD· 2 shared André‐Dante DurhamiD· 1 shared Antoine Job· 1 shared Enikö A. KramáriD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

Benoît PetitORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintNov 1, 2026

✦ In-depth digest

Differential and regionally distinct molecular responses distinguish FLASH and conventional RT in a medulloblastoma model while preserving therapeutic outcomes

Michèle Knol, Javier Franco‐Pérez, Aymeric Almeida…·Paola Ballesteros‐Zebadúa

Hypo-fractionated FLASH and conventional radiotherapy (3x10 Gy) each ablated orthotopic human medulloblastoma in nude mice; FLASH evoked distinct microglial and hippocampal transcriptional programs and less neuroinflammation.

DOI 10.64898/2026.03.16.712103

mousehuman

𝕏 PostBluesky

Cancer BiologybioRxivPreprintNov 1, 2026

Dosimetric Characterization and Workflow Optimization of the FLASH-SARRP for Reliable Preclinical Radiobiological Studies

Michèle Knol, Patrik Gonçalves Jorge, L. L. Kunz…·Julie Lascaud

This paper characterizes the FLASH-SARRP irradiator and validates a QA workflow to improve dose reproducibility in preclinical FLASH experiments.

DOI 10.64898/2026.07.06.736680

experimental assay

𝕏 PostBluesky

Cancer BiologybioRxivPreprintMay 19, 2026

Neuroprotection following FLASH-RT may be mediated by sustained glutamate receptor AMPAR activation in CA3 neurons

Louis V. Kunz, Aymeric Almeida, Michèle Knol…·Marie‐Catherine Vozenin

This study investigates FLASH-RT's neuroprotective effects by showing sustained AMPAR activation in CA3 neurons through early transcriptional upregulation of glutamate receptor genes.

DOI 10.64898/2026.05.15.725423

mousebulk RNA-seq

𝕏 PostBluesky