Peripheral Artery Disease Management

Foot perfusion. Insights from an anatomically detailed arterial network model

This paper models foot perfusion during a cuff-induced ischaemia test to assess how arterial occlusions and collateral impairment affect tissue perfusion in different foot regions.

Genome-Wide Association Study of Genetic Variants Associated with Lower Extremity Amputation Risk in Peripheral Artery Disease

This study identifies genetic variants associated with lower extremity amputation risk in peripheral artery disease using GWAS from the All of Us Research Program.

BIOMECHANICAL CHARACTERIZATION OF PORCINE LOWER LIMB ARTERIES FOR PRECLINICAL EVALUATION OF PERIPHERAL VASCULAR DEVICES

This study characterizes the biomechanical properties of porcine lower limb arteries to evaluate their suitability as preclinical models for peripheral vascular devices.

PAD-associated genetic variants are more strongly associated with surgical intervention than premature onset

This study identifies PAD-associated SNPs with stronger associations with surgical intervention than premature onset using UK Biobank data.

Evaluation of plasma biomarkers for causal association with peripheral artery disease

This paper evaluates plasma biomarkers for causal association with peripheral artery disease using Mendelian randomization, identifying 19 biomarkers with significant genetic evidence for causality.

Admixture Mapping of Peripheral Artery Disease in a Dominican Population Reveals a Novel Risk Locus on 2q35

The paper identifies a novel risk locus for PAD on 2q35 in Dominicans using admixture mapping and health systems data.