Physics-Driven Zero-Shot Reconstruction of Isotropic 3D Fluorescence Microscopy under Undersampled Acquisition
Ruijie Cao, Tong Jin, Fengyuan Xin, Yiwei Hou, You Fu, Boya Jin, Lijun Li, Shu Gao, Han Wang, Yaning Li, Dilizhatai Saimi, Wei Ren, Wenyi Wang, Guangwei Xin, Kexin Yuan, , Peng Xi
This paper introduces DeepUI, a physics-driven framework that reconstructs isotropic 3D fluorescence images from undersampled axial data, achieving high performance even under challenging conditions.
bioRxiv · Jun 16, 2026 · PreprintBioinformatics