Svenja Caspers

Functional and Structural Brain Age Gaps as Complementary Predictive Markers for Cognitive Performance

The paper predicts structural and functional brain age gaps from MRI data to assess their predictive power for cognitive performance in healthy adults.

Structural integrity moderates the cognitive bearing of dopamine clearance in aging

The paper develops ADAM, a model linking dopamine clearance and structural connectivity to cognitive aging, finding elevated clearance timescales and a structure-age-dependent association with cognitive performance.

Linking human brain functional connectivity to underlying neurotransmitter systems

This study links human brain functional connectivity to neurotransmitter systems using resting-state fMRI and MEG across multiple cohorts, showing consistent patterns and clinical relevance.

The Uniqueness of Human Vulnerability to Brain Aging in Great Ape Evolution

The paper compares age-related brain deterioration between humans and chimpanzees, finding a unique positive relationship between cerebral aging and cortical expansion in humans.

Genetic variants for head size share genes and pathways with cancer

This study identifies 67 genetic loci associated with head size, finding strong overlaps with cancer pathways and genes, suggesting shared genetic mechanisms between head growth and cancer risk.

Resting state changes in aging and Parkinson's disease are shaped by underlying neurotransmission - a normative modeling study

The paper uses normative modeling and neurotransmitter mapping in the UK Biobank to show how age and Parkinson's disease affect brain resting state activity and connectivity through specific neurotransmitter systems.

Towards robust and generalizable super-resolution generative adversarial networks for magnetic resonance neuroimaging: a cross-population approach

This paper demonstrates that SRGANs can generalize across different populations in MRI without introducing artifacts, showing robustness in real-world applications.

The virtual aging brain: a model-driven explanation for cognitive decline in older subjects

This paper develops a causal inference framework to link structural connectivity and brain function in aging, showing increased structural modulation in poor cognitive performers.

Occipital Intralobar fasciculi and a novel description of three forgotten tracts

This paper provides a modern description of occipital intralobar fiber tracts using diffusion MRI tractography, reconstructing five tracts described by Dejerines and identifying a sixth.

Genetic factors influencing a neurobiological substrate for psychiatric disorders

The paper investigates genetic factors influencing a neurobiological substrate for psychiatric disorders and finds that a common genetic variant is associated with the substrate but not directly with disease risk.

The role of thickness inhomogeneities in hierarchical cortical folding

This study uses simulations to show that thickness inhomogeneities in the brain's cortex lead to complex folding patterns, resembling higher-order brain structures.

Chimpanzee Brain Morphometry Utilizing Standardized MRI Preprocessing and Macroanatomical Annotations

This study develops a chimpanzee brain reference template and processing pipeline to analyze structural MRI data, revealing age-related GM atrophy and hemispheric asymmetry patterns.

Age-related changes of Peak width Skeletonized Mean Diffusivity (PSMD) across the adult life span: a multi-cohort study

This study examines age-related changes in PSMD across the adult lifespan using multi-cohort diffusion tensor imaging data, finding PSMD increases consistently while other metrics show different age patterns.

Neural Correlates of Motor Imagery, Action Observation, and Movement Execution: A Comparison Across Quantitative Meta-Analyses

Coordinate-based meta-analyses reveal a premotor, rostral parietal, and somatosensory core shared by motor imagery, action observation, and execution; only imagery and execution share putamen and cerebellum.