Jun Qian

This paper reports a new two-photon fluorescence mechanism in organic dyes mediated by singlet states, validated across multiple dyes and applied to imaging mouse and human tissues.

This paper introduces NFR, a prior-free algorithm that enhances microscopy resolution without requiring PSF estimation, achieving results beyond the Sparrow limit and improving super-resolution techniques.

This study uses NIR-II fluorescence confocal microscopy to observe fast chloroplast dynamics in intact leaves, revealing rapid avoidance responses in submerged leaves to red light.

This paper develops a neural network to reduce photodamage in three-photon microscopy, enabling faster and safer imaging of muscle regeneration.

This paper develops a TIS window technique for long-term high-resolution cortical imaging in awake mice without skull removal.

This paper combines skull optical clearing and three-photon microscopy to achieve deep brain imaging through an intact mouse skull.

This study demonstrates AIE nanoparticles enabling ultra-deep three-photon imaging in live mouse brains using NIR-IIa excitation.

The paper develops NIR-II fluorescence microscopy techniques to image cortical vasculature in non-human primates, enabling high-resolution analysis of brain microvascular networks and blood flow.