Transplantation: Methods and Outcomes

Predicting Primary Graft Dysfunction in Lung Transplantation: Machine Learning-Guided Biomarker Discovery

This study uses machine learning to identify cytokines predictive of primary graft dysfunction in lung transplantation, finding BAL fluid at 2h post-transplant as the strongest predictor.

Single-nuclear RNA sequencing of endomyocardial biopsies identifies persistence of donor-recipient chimerism with distinct signatures in severe cardiac allograft vasculopathy

Identification of Cell-Free DNA Methylation Patterns Unique to the Human Left Ventricle as a Potential Indicator of Acute Cellular Rejection

The paper identifies ventricle-specific DNA methylation patterns in cell-free DNA that correlate with acute cellular rejection in heart transplant recipients.

Donor-derived mitochondrial DNA variant peptides elicit allo-specific immune response in transplant patients

This study shows donor-derived mitochondrial DNA variants trigger allo-specific immune responses in transplant patients, with higher IFN-gamma release compared to recipient-derived peptides.