Cell surface proteomics of patient-derived malignant rhabdoid tumor organoids identifies ROBO1 as potential CAR T cell target for pediatric solid tumors.
Juliane L. Buhl, Jannet Koelewijn, Charlotte op ’t Hoog…·Claudia Y. Janda
Topic · Oncology · Medicine
OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.
4 papers
Juliane L. Buhl, Jannet Koelewijn, Charlotte op ’t Hoog…·Claudia Y. Janda
Chaido Stathopoulou, Mingming Zhao, Qun Jiang…·Raffit Hassan
This study tracks the temporal changes in the tumor microenvironment after nanobody-based CAR-T therapy, revealing dynamic gene expression shifts and identifying potential therapeutic targets.
Erik Rihtar, Tina Fink, Monika Belak…·Roman Jerala
This paper develops a pharmacologically controlled system for regulating CAR T cell function using estrogen receptor-based degron domains and FDA-approved compounds.
Kyle B. Lupo, M. Kazim Panjwani, Aya G. Halawi…·Katharine C. Hsu
This study shows that engineered NKG2C+ NK-like T cells have better antitumor effects and lower cytokine release syndrome risk than conventional CAR-T and CAR-NK cells.