Aldose Reductase and Taurine

A sensitive fluorometric assay to detect aldo-keto reductase and carbonyl reductase activity based on a naphthaldehyde derivative

This paper introduces a fluorometric assay for detecting reductase activity using MONOL-41, showing improved sensitivity and lower detection limits compared to NADPH-based methods.

Hepatic aldose reductase drives a Warburg effect-like metabolic reprogramming to promote insulin resistance, fatty liver and obesity

This study shows that hepatic aldose reductase activation causes metabolic reprogramming similar to the Warburg effect, leading to insulin resistance, fatty liver, and obesity.