Topic · Epidemiology · Medicine

Multiple and Secondary Primary Cancers

OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.

2 papers

Mutational footprint of platinum chemotherapy in a secondary thyroid cancer

Julia Schiantarelli, Θεοδώρα Παππά, Jake R. Conway, Jett P. Crowdis, Brendan Michael Reardon, Felix Dietlein, Julian Huang, Darren A. Stanizzi, Evan Carey, Alice Bosma-Moody, Alma Imamović, Seunghun Han, Sabrina Yvonne Camp, Eric R. Kofman, Erin E. Shannon, , Eliezer M. Van Allen

This paper reports a case where platinum chemotherapy exposure was linked to the development of aggressive thyroid cancer through mutational signatures and genomic analysis.

JCO Precision Oncology · Aug 1, 2022Peer-reviewedGenomics

Risk of multiple primary cancer diagnosis over age in families of Li-Fraumeni syndrome: a single institution perspective

Seung Jun Shin, Elissa B. Dodd-Eaton, Fan Gao, Jasmina Bojadzieva, Jingxiao Chen, Xianhua Kong, Christopher Ian Amos, Jing Ning, Louise C. Strong, Wenyi Wang

The paper estimates penetrance for first and second primary cancer diagnoses in Li-Fraumeni syndrome families and validates a risk prediction model with an AUC of 0.77.

Cancer Research · Nov 12, 2019Peer-reviewedGenetics