Explore 363,000 bioRxiv and medRxiv papers across 26 biological disciplines. Save private star ratings to train your personal recommendation feed, curate reading collections, and check community reproducibility reports before building on a paper's code.
Charlotte Crauwels, Adrián Díaz, Wim Vranken
Resource of 212 literature-curated chimeric class A GPCRs linked to 1,755 natural class A mammalian GPCRs, annotated at sequence, structure and biophysics level, with guidelines for designing new chimeras.
Journal of Molecular Biology · Apr 21, 2025Peer-reviewedBioengineering✦ In-depth digest
Thibault Vervenne, Mathias Peirlinck, Nele Famaey, Ellen Kuhl A
Constitutive artificial neural networks trained on biaxial tests of 8 ovine main pulmonary artery samples consistently discover a two-term model: exponential first-invariant plus quadratic fifth-invariant terms.
Biomechanics and Modeling in Mechanobiology · Feb 24, 2025Peer-reviewedBioengineering✦ In-depth digest
Reese A. Dunne, Ethan C. Darwin, Valerie A. Perez Medina, Marc E. Levenston, Skyler R. St. Pierre, Ellen Kuhl A
Plant-based products span stiffness 56.65 kPa (firm tofu) to 418.9 kPa (Tofurky roast), bracketing three processed animal meats; stiffness plus shear storage and loss moduli were the most consistent readouts.
Food Research International · Feb 4, 2025Peer-reviewedBioengineering✦ In-depth digest
Aubin Ramon, Mingyang Ni, Olga Predeina, Rebecca Gaffey, Patrick Kunz, Shimobi C. Onuoha, Pietro Sormanni
NanoMelt, a ridge-stacked ensemble of regressors on four diverse sequence embeddings, predicts nanobody melting temperature from 640 curated sequences, reaching Spearman 0.832 under nested cross-validation.
mAbs · Jan 8, 2025Peer-reviewedBioengineering✦ In-depth digest
Skyler R. St. Pierre, Lauren Somersille Sibley, Steven Tran, Vy Tran, Ethan C. Darwin, Ellen Kuhl A
Plant-based deli slices are over twice as stiff as animal deli meats under biaxial tension; stiffness tracks brittleness rated by 18 tasters (ρ = 0.857).
Current Research in Food Science · Jan 1, 2025Peer-reviewedBioengineering✦ In-depth digest
Jason Derks, Andrew Leduc, Georg Wallmann, R. Gray Huffman, Matthew Willetts, Saad Khan, Harrison Specht, Markus Ralser, Vadim Demichev, Nikolai Slavov
Multiplexing nonisobaric isotopologous mass tags (mTRAQ) with data-independent acquisition and DIA-NN increases sensitive proteomics throughput 3-fold while cutting missing data below 3% in bulk and single cells.
Nature Biotechnology · Jul 14, 2022Peer-reviewedBioengineering✦ In-depth digest
Bogdan Budnik, Ezra Levy, Guillaume Harmange, Nikolai Slavov
SCoPE-MS combines acoustic cell lysis with isobaric tandem-mass-tag carrier channels to quantify over a thousand proteins in single mammalian cells, resolving cancer cell types and stem cell differentiation.
Genome biology · Oct 9, 2018Peer-reviewedBioengineering✦ In-depth digest