Discover, rate, and discuss biology preprints.

This paper develops a stochastic framework for modeling multivariate trait evolution, showing drift causes directional shifts in genetic covariance matrices, contrasting with common assumptions.

This study shows that ridge and crossrib height in butterfly wing scales influence structural color diversity and introduces a geometrical model to predict color.

This paper develops a new mathematical framework, ProP Gen, to model evolutionary dynamics under phenotypic uncertainty and shows it explains phenomena like phenotypic buoying and improves predictions of bacterial persistence.

This study experimentally evolves yeast to show that mutations beneficial in early stationary phase are detrimental in late stationary phase, indicating a fitness trade-off.

The paper introduces a phylogenetic model, RFBS, to distinguish between established and enabled biome affinities in species evolution and applies it to flowering plants.

This study shows temperature stress disrupts coevolution in a microbial predator-prey system by limiting trait evolution in both species.

This study identifies cis-regulatory evolution as a key mechanism driving dehydration response variation in desert-adapted house mice.

The paper develops a Bayesian method to detect gene flow between sister lineages, showing it has low false-positive rates and high power, and applies it to Sceloporus lizards data.

This paper proposes a thermoregulatory theory linking endothermy to reduced regenerative capacity in mammals and birds, suggesting that calcium signaling in thermogenic systems inhibits tissue repair.

The paper tests if song divergence between two populations of Canary Islands Chaffinches acts as a pre-mating barrier, finding weak behavioural discrimination between habitats.

The study finds that Varroa destructor mites from varroa-resistant honey bee colonies are consistently smaller than those from non-resistant colonies across Europe.

The paper shows that maternal behavioral noise drives phenotypic variation in pea aphids by accumulating environmental cues, linking stochastic behavior to morphological plasticity.

This paper introduces SHEPHERD, a method combining population genetics and MDPs to design adaptive drug policies that reduce disease fitness in heterogeneous populations, showing effectiveness in synthetic multi-drug landscapes.

The paper quantifies phylogenetic signal in primate ontogeny, finding dental development is most conserved, with later-developing traits showing stronger conservation than earlier ones.

The paper analyzes mutation spectra across 108 eukaryotic species, revealing cytosine transition mutability at CpG and CHG sites as key drivers of variation, with methylation levels not predicting mutation rates.

This study compares adaptive routes in two yeast species after 10,000 generations, finding parallel but distinct molecular mechanisms of adaptation.

This paper describes the discovery of a new marine Stentor species, Stentor hondawara, and reports its whole-genome analysis revealing unique ecological adaptations compared to freshwater Stentor species.

This study tests the redox theory of aging by evolving mosquitoes under different reproductive schedules and parasite exposure, finding that oxidative stress contributes but does not determine aging.

The paper develops a method to infer directional migration rates from ancient DNA data using time-dependent F2 statistics, revealing an ancient pan-European migration network.