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363,000+ bioRxiv and medRxiv preprints, including those later published in peer-reviewed journals, across 26 biological disciplines.
Recent preprints
- Evolutionary BiologybioRxivPreprint
Ablation of the evolutionarily acquired functions of the Atp1b4 gene in mice protects against obesity and increases metabolic capacity
Nikolaï N. Modyanov, Lucia Russo, Sumona L. Ghosh…·Ivana L. de la Serna
This study shows that ablating the Atp1b4 gene in mice reduces obesity and improves metabolic parameters by disrupting evolutionarily acquired BetaM functions.
DOI 10.1101/2025.02.26.640446 - Evolutionary BiologyNature CommunicationsPeer-reviewed
Interpreting mammalian evolutionary constraint at synonymous sites in light of the unwanted transcript hypothesis
Matthew J. Christmas, Michael X. Dong, Jennifer R. S. Meadows…·Kerstin Lindblad‐Toh
The paper examines mammalian evolutionary constraint at synonymous sites, finding significant constraint in 20.8% of four-fold degenerate sites and biases toward G/C content and splice sites.
- Evolutionary BiologybioRxivPreprint
Optimal cues for transmission investment in malaria parasites
Avril Luyang Wang, Megan A. Greischar, Nicole Mideo
This study identifies optimal environmental cues for malaria parasites to maximize reproductive success by analyzing how different cues affect transmission investment strategies.
DOI 10.1101/2025.02.26.640285 - Evolutionary BiologybioRxivPreprint
Repeatable phenotypic but not genetic response to selection on body size in the black soldier fly
Tomas N. Generalovic, Wenjun Zhou, Leia Chengcheng Zhao…·Chris D. Jiggins
The paper selects for large body size in black soldier flies and finds repeatable phenotypic but not genetic responses, highlighting high genetic redundancy in polygenic traits.
- Evolutionary BiologyMolecular EcologyPeer-reviewed
Overcoming ploidy barriers: the role of triploid bridges in the genetic introgression of Cardamine amara
Paolo Bartolić, Alena Voltrová, Lenka Macková…·Filip Kolář
This study shows triploid hybrids facilitate gene flow between diploid and tetraploid Cardamine amara populations, overcoming ploidy barriers through bidirectional introgression.
- Evolutionary BiologyComparative CytogeneticsPeer-reviewed
Rapid Changes in Chromosome Counts in Fishes from the Spiral Egg Clade within the Gourami Family (Osphronemidae).
Brendan Mobley, Andrew P. Anderson
The paper reports rapid chromosomal changes in spiral egg clade fishes, finding high variability in chromosome counts and arm numbers, suggesting rapid chromosome loss and large-scale mutations.
DOI 10.3897/compcytogen.19.132971 - Evolutionary BiologyThe ISME JournalPeer-reviewed
Genome diversification of symbiotic fungi in beetle-fungus mutualistic symbiosis
Yin‐Tse Huang, Khaled Abdrabo El‐Sayid Abdrabo, Guan Jie Phang…·Jiří Hulcr
This study examines genomic adaptations of ambrosia fungi across multiple lineages, finding lineage-specific changes rather than genome-wide reductions or convergent evolution.
- Evolutionary BiologybioRxivPreprint
Evolutionary History of Treponema pallidum subsp. pertenue: Insights into Host Ancestry and Cross-Species Transmission
Sabrina Karolaine Araújo Sousa de Lima, Tetsu Sakamoto
This study analyzes TPE genome sequences to investigate host ancestry and cross-species transmission, finding limited interaction between human and non-human primate infections.
DOI 10.1101/2025.02.25.640066 - Evolutionary BiologyPLoS BiologyPeer-reviewed
Evolutionary origin of synovial joints
Neelima Sharma, Yara Haridy, Neil H. Shubin
This study identifies synovial joints in elasmobranchs but not cyclostomes, suggesting their origin in the common ancestor of jawed vertebrates.
6 citations - Evolutionary BiologyAmerican Journal of BotanyPeer-reviewed
Phylogenomics of the North American Desert Radiation Linanthus (Polemoniaceae) Reveals Mixed Trait Lability and No Single Geographic Mode of Speciation
Ioana G. Anghel, Lydia L. Smith, Isaac H. Lichter‐Marck, Felipe Zapata
This study uses genomic data to reconstruct the evolutionary history of Linanthus species, revealing complex speciation patterns and trait evolution in arid environments.
- Evolutionary BiologybioRxivPreprint
High genomic stability of wMel Wolbachia after introgression into three geographically distinct Aedes aegypti populations
Kimberley R. Dainty, Jane Hawkey, Endah Supriyati…·Heather A. Flores
The study tracks genomic changes in wMel Wolbachia over six years in three Aedes aegypti populations and finds minimal evolution, supporting its stability as a biocontrol agent.
DOI 10.1101/2025.02.24.638572 - Evolutionary BiologybioRxiv
ERC 2.0 - evolutionary rate covariation update provides more powerful inference of functional interactions across large phylogenies
Jordan Little, G. Meyer, Aakash Grover…·Maria D. Chikina
ERC2.0 improves functional interaction prediction across large phylogenies by enhancing algorithm speed, normalization, and statistical power.
- Evolutionary BiologybioRxivPreprint
Accelerated genome shuffling associated with rapid evolution of sexual conflict in seed beetles
Weiyao Chen, Jinshuai Zhao, Miaojin Lin…·Jinfeng Chen
The paper investigates structural variants in seed beetles, linking them to rapid evolution of sex chromosomes and sex-biased gene expression.
DOI 10.1101/2025.02.24.639998 - Evolutionary BiologybioRxivPreprint
Latitudinal phylogenetic and diversity gradients are explained by a tropical-temperate transitional region
David R. Lerner, Jason T. Weir, Tamir Klein, Gili Greenbaum
The paper identifies a previously unknown bioregion between tropical and temperate zones that explains latitudinal biodiversity and phylogenetic gradients through simulations.
DOI 10.1101/2025.02.23.639794 - Evolutionary BiologybioRxivPreprint
A network-based comparative method to study reptile scalation and other homologous two-dimensional patterns
The paper introduces a network-based method to compare homologous two-dimensional patterns, demonstrating its application to reptile scalation patterns.
DOI 10.1101/2025.02.23.639519 - Evolutionary BiologybioRxivPreprint
Clonal interference, genetic variation and the speed of evolution in structured populations
Yang Ping Kuo, Jiewen Hu, Oana Carja
This study shows that heterogeneous population structures can increase evolutionary rates and alter genetic variation dynamics, challenging prior assumptions about structured populations slowing evolution.
2 citations - Evolutionary BiologyJournal of Integrative Plant BiologyPeer-reviewed
Evidence for evolution of a new sex chromosome within the Marchantiales haploid-dominant plant lineage
Yuan Fu, Xiaoxia Zhang, Tian Zhang…·Bo Xu
The paper investigates dioicy-monoicy transitions in liverworts, confirming monoicy evolved from a dioicous ancestor and describing potential re-evolution of dioicy with new sex chromosome formation.
- Evolutionary BiologyScientific ReportsPeer-reviewed
Natural slab photonic crystals and where to find them among the girdle bands of diatoms
Matt Peter Ashworth, Daryl W. Lam, Martín López‐García…·Johannes W. Goessling
The paper identifies slab photonic crystals in diatom girdle bands using FFT analysis across 393 SEM images, revealing their distribution and photonic properties across taxonomic groups.
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