Molecular BiologyeLifePeer-reviewed
PUMILIO hyperactivity drives premature aging of Norad-deficient mice
Florian B. Kopp, Mehmet Emir YALVAÇ, Beibei Chen…·Joshua T. Mendell
This study shows that loss of the lncRNA Norad leads to PUMILIO hyperactivity, causing genomic instability and mitochondrial dysfunction, resulting in premature aging in mice.
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