Author

Mehmet Emir YALVAÇ

Nationwide Children's HospitalORCID 0000-0001-6262-1476Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

Beibei Chen· 1 shared Benedict S. KhooiD· 1 shared Florian B. KoppiD· 1 shared Frank A GillettiD· 1 shared He ZhangiD· 1 shared Hongtao YuiD· 1 shared Joshua T. MendelliD· 1 shared K. John McLaughlin· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMolecular Biology

Beibei Chen

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2 papers

Recent·Most cited

Molecular BiologyFrontiers in GeneticsPeer-reviewedApr 6, 2021

Adapting CRISPR/Cas9 System for Targeting Mitochondrial Genome

Syed-Rehan A. Hussain, Mehmet Emir YALVAÇ, Benedict S. Khoo…·K. John McLaughlin

This study demonstrates a method to edit mitochondrial DNA using CRISPR-Cas9 by modifying guide RNA with a stem loop element for mitochondrial targeting.

102 citationstop 2%

humanCRISPR screen

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Molecular BiologyeLifePeer-reviewedFeb 8, 2019

PUMILIO hyperactivity drives premature aging of Norad-deficient mice

Florian B. Kopp, Mehmet Emir YALVAÇ, Beibei Chen…·Joshua T. Mendell

This study shows that loss of the lncRNA Norad leads to PUMILIO hyperactivity, causing genomic instability and mitochondrial dysfunction, resulting in premature aging in mice.

98 citationstop 4%

mouseDNA methylation

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