Author

Mahmoud M. Elguindy

The University of Texas Southwestern Medical CenterORCID 0000-0001-9151-1751Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:DNA methylation· 1 Organism:human· 1 Assay:long-read sequencing· 1

Frequent Co-Authors

Florian B. KoppiD· 2 shared Joshua T. MendelliD· 2 shared Anu Alice ThomasiD· 1 shared Beibei Chen· 1 shared Frank A GillettiD· 1 shared Frederick RehfeldiD· 1 shared He ZhangiD· 1 shared Hongtao YuiD· 1 shared

Activity by Year

2019-2019 · peak 2/yr

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10 top collaborators · 30 mutual co-author links

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2 shared papersMolecular Biology

Florian B. KoppORCID

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2 papers

Recent·Most cited

Molecular BiologyeLifePeer-reviewedJul 25, 2019

PUMILIO, but not RBMX, binding is required for regulation of genomic stability by noncoding RNA NORAD

Mahmoud M. Elguindy, Florian B. Kopp, Mohammad Goodarzi…·Joshua T. Mendell

This study shows that NORAD's interaction with PUMILIO, not RBMX, is essential for maintaining genomic stability in mammals.

81 citationstop 3%

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Molecular BiologyeLifePeer-reviewedFeb 8, 2019

PUMILIO hyperactivity drives premature aging of Norad-deficient mice

Florian B. Kopp, Mehmet Emir YALVAÇ, Beibei Chen…·Joshua T. Mendell

This study shows that loss of the lncRNA Norad leads to PUMILIO hyperactivity, causing genomic instability and mitochondrial dysfunction, resulting in premature aging in mice.

98 citationstop 4%

mouseDNA methylation

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