Structural Basis for Dimeric Genome Selection by HIV-1
Nele Merret Hollmann, Siarhei Kharytonchyk, A Buchanan, Caela Phillips, Amir Ledbetter, Fairine Ahmed, Anna Adelstein, Kaylee Barry, Samuel A. Geleta, Cleo Burnett, Alice Telesnitsky, Barbie K. Ganser‐Pornillos, Owen Pornillos, Michael F. Summers
This study identifies how dimeric HIV-1 RNA structures facilitate Gag protein assembly, revealing a structural mechanism for genome packaging.
bioRxiv · Jun 18, 2026 · PreprintMolecular Biology