Alice Telesnitsky

This study identifies how dimeric HIV-1 RNA structures facilitate Gag protein assembly, revealing a structural mechanism for genome packaging.

This study shows that the adenosine-rich content of the HIV-1 genome is critical for efficient packaging, as demonstrated by Gag-SRSF5 chimera experiments.

This study shows that HIV-1 silencing in polyclonal cell populations arises from clone-specific behaviors, not uniform repression, with many clones maintaining stable bimodal expression over time.

This study shows that MDA5 senses HIV-1 unspliced RNA based on 5' cap structure and nuclear export pathway, revealing how the virus evades innate immunity.

This study examines HIV-1 mutants that produce only one transcription start site RNA and finds that they display complementary replication functions restored by reversion.

The paper identifies HIV-1's use of heterogeneous transcription start sites (TSSs) for RNA fate determination, showing it differs from other retroviruses and is mediated by core promoter elements.