Author

A. A. Hussien

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

J. G. Snedeker· 3 shared B. Niederoest· 2 shared F. Renoux· 1 shared G. Moschini· 1 shared J. Foolen· 1 shared K. De Bock· 1 shared M. Bollhalder· 1 shared N. Goedecke· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersBioengineering

J. G. Snedeker

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3 papers

Recent·Most cited

IL-6 SIGNALING EXACERBATES HALLMARKS OF CHRONIC TENDON DISEASE BY STIMULATING REPARATIVE FIBROBLASTS

T. Stauber, G. Moschini, A. A. Hussien, P. K. Jaeger, K. De Bock, J. G. Snedeker

This study identifies IL-6 signaling as a driver of chronic tendon disease by activating reparative fibroblasts and promoting tendinopathy hallmarks.

bioRxiv · Feb 13, 2023Bioengineering

Sustained mechanical tension governs fibrogenic activation of tendon stromal cells in systemic sclerosis

A. A. Hussien, R. Knell, F. Renoux, S. Wunderli, B. Niederoest, J. Foolen, O. Distler, J. G. Snedeker

This study shows that sustained mechanical tension drives fibrogenic activation of tendon stromal cells in systemic sclerosis, revealing a feedback loop between fibroblasts and ECM stiffening.

bioRxiv · Jun 11, 2021Cell Biology

The stiffness-sensitive transcriptome of human tendon stromal cells

A. A. Hussien, B. Niederoest, M. Bollhalder, N. Goedecke, J. G. Snedeker

This study maps how matrix stiffness influences the transcriptome of human tendon stromal cells, revealing distinct gene expression programs at different stiffness levels.

bioRxiv · May 27, 2021Bioengineering