Opposing activities of IFITM proteins in SARS-CoV-2 infection
G. Shi, A. D. Kenney, E. Kudryashova, L. Zhang, L. Hall-Stoodley, R. Robinson, D. Kudryashov, A. A. S. Compton, J. S. Yount
This study identifies opposing roles of IFITM3 in restricting and enhancing SARS-CoV-2 infection through distinct mechanisms involving endosomal restriction and plasma membrane fusion.
bioRxiv · Aug 11, 2020Immunology