Author

A. Alay

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

X. Sole· 2 shared A. Dawson· 1 shared A. Esteve-Codina· 1 shared A. G. Jochemsen· 1 shared A. M. Valverde· 1 shared A. Sanchez· 1 shared A. Sharkley· 1 shared A. Teunisse· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

X. Sole

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The hepatocyte Epidermal Growth Factor Receptor (EGFR) pathway regulates the cellular interactome within the liver fibrotic niche

E. Gonzalez-Sanchez, J. Vaquero, D. Caballero-Diaz, J. Grzelak, N. P. Fuste, E. Bertran, J. Amengual, J. Garcia-Saez, B. Martin-Mur, M. Gut, A. Esteve-Codina, A. Alay, C. Coulouarn, S. Calero, P. Valdecantos, , I. Fabregat

This study shows that inhibiting EGFR in hepatocytes reduces liver fibrosis by altering immune cell populations and molecular mechanisms involved in inflammation and fibrogenesis.

bioRxiv · Nov 3, 2023Pathology

Efficacy of CDK4/6 inhibitors in preclinical models of malignant pleural mesothelioma

E. Aliagas, A. Alay, M. Martinez-Iniesta, M. Hernandez-Madrigal, D. Cordero, M. Gausachs, E. Pros, M. Saigi, S. Busacca, A. Sharkley, A. Dawson, R. Palmero, S. Padrones, S. Aso, I. Escobar, , E. Nadal

This study evaluates CDK4/6 inhibitors in preclinical models of malignant pleural mesothelioma, finding they reduce tumor growth and improve survival by inducing cell cycle arrest and senescence.

bioRxiv · Feb 8, 2021 · PreprintCancer Biology

Breast cancer dormancy is associated with a 4NG1 state and not senescence

C. Prunier, A. Alay, M. van Dijk, K. L. Ammerlaan, S. van Gelderen, D. L. Marvin, A. Teunisse, R. C. Slieker, K. Szuhai, A. G. Jochemsen, X. Sole, P. ten Dijke, L. Ritsma

The paper characterizes breast cancer dormancy in cell lines, showing D2.OR cells enter a 4NG1 state rather than senescence, and can be reversed.

bioRxiv · Nov 20, 2020Cell Biology