A mathematical dissection of the adaptation of cell populations to fluctuating oxygen levels
A. Ardaseva, R. A. Gatenby, A. R. A. Anderson, H. M. Byrne, P. K. Maini, T. Lorenzi
The paper uses a phenotype-structured model to show how fluctuating oxygen levels affect cell population dynamics and competitive advantage through phenotypic variation rates.
bioRxiv · Mar 9, 2020Cancer Biology