CRISPR-based screens uncover determinants of immunotherapy response in Multiple Myeloma
P. Ramkumar, A. B. Abarientos, R. Tian, M. Seyler, J. T. Leong, M. Chen, P. Choudhry, T. Hechler, N. Shah, S. W. Wong, T. G. Martin, J. L. Wolf, K. T. Roybal, A. Pahl, J. Taunton, , M. Kampmann
This study uses CRISPR screens to identify mechanisms increasing BCMA expression and enhancing anti-myeloma efficacy of BCMA-targeted therapies in multiple myeloma.
bioRxiv · Apr 14, 2020Cancer Biology