Selective G protein signaling driven by Substance P-Neurokinin Receptor structural dynamics
J. A. Harris, B. Faust, A. B. Gondin, M. A. Damgen, C.-M. Suomivuori, N. A. Veldhuis, Y. Cheng, R. O. Dror, D. M. Thal, A. Manglik
This study investigates how different agonists of the NK1R receptor influence G-protein signaling through structural dynamics and extracellular loop interactions.
bioRxiv · May 16, 2021Biochemistry