C.-M. Suomivuori

The paper determines the cryo-EM structure of active GPR161 bound to Gs, revealing sterol binding and its role in ciliary cAMP signaling, while showing that sterol binding is not essential for Hedgehog pathway suppression.

This study investigates how endocannabinoids modulate CB1 receptor signaling by comparing their activation of Gi1 with synthetic cannabinoids and revealing structural differences in ligand binding.

This study investigates how different agonists of the NK1R receptor influence G-protein signaling through structural dynamics and extracellular loop interactions.