Targeting the mTORC2 signaling complex in B cell malignancies.
W. Liao, G. Jordaan, A. Benavides-Serrato, B. Holmes, J. Gera, S. Sharma
This study identifies novel inhibitors that disrupt the mTORC2 complex and induce apoptosis in chronic lymphocytic leukemia cells more effectively than existing treatments.
bioRxiv · Mar 5, 2019 · PreprintCancer Biology