mTORC2/AKT/HSF1/HuR Constitute A Feed-Forward Loop Regulating Rictor Expression And Tumor Growth In Glioblastoma
B. Holmes, A. Benavides-Serrato, R. S. Freeman, K. A. Landon, T. Bashir, R. N. Nishimura, J. Gera
This study identifies a feed-forward loop involving mTORC2/AKT/HSF1/HuR that regulates Rictor expression and promotes glioblastoma growth.
bioRxiv · May 19, 2017Cancer Biology