Author

R. N. Nishimura

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:gene regulatory network inference· 1 Assay:metagenomics· 1

Frequent Co-Authors

J. E. Hansen· 3 shared J. Gera· 3 shared A. Shirali· 2 shared A. Benavides-Serrato· 1 shared A. Ebens· 1 shared B. Holmes· 1 shared B. J. Cuffari· 1 shared C. Hino· 1 shared

Activity by Year

2017-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersImmunology

J. E. Hansen

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

DNA-targeting and cell-penetrating antibody-drug conjugate

A. Shirali, V. Dubljevic, F. Cao, R. N. Nishimura, A. Ebens, J. A. Campbell, J. E. Hansen

The paper develops a DNA-targeting antibody-drug conjugate that selectively kills BRCA2-deficient tumors while sparing DNA repair-proficient ones.

bioRxiv · Apr 12, 2023 · PreprintImmunology

Cellular protection from H2O2 toxicity by Fv-Hsp70 and mutants of Fv-Hsp70. Protection via catalase and gamma-glutamyl cysteine synthase.

C. Hino, G. Chan, G. Jordaan, S. S. Chang, J. Saunders, M. T. Bashir, J. E. Hansen, J. Gera, R. H. Weisbart, R. N. Nishimura

This study shows Fv-Hsp70 and its mutants protect SH-SY5Y cells from H2O2 toxicity through a protein-binding domain, and this protection involves catalase and gamma-glutamylcysteine synthase.

bioRxiv · Feb 22, 2023 · PreprintCell Biology

cGAS-activating lupus autoantibody for cancer immunotherapy

X. Chen, X. Tang, B. J. Cuffari, C. Tang, X. Gao, P. W. Noble, M. R. Young, O. M. Turk, A. Shirali, J. Gera, R. N. Nishimura, J. Zhou, J. E. Hansen

This study shows a lupus anti-DNA autoantibody activates cGAS and improves survival in glioblastoma models by enhancing CD8+ T cell infiltration.

bioRxiv · Feb 11, 2023 · PreprintImmunology

mTORC2/AKT/HSF1/HuR Constitute A Feed-Forward Loop Regulating Rictor Expression And Tumor Growth In Glioblastoma

B. Holmes, A. Benavides-Serrato, R. S. Freeman, K. A. Landon, T. Bashir, R. N. Nishimura, J. Gera

This study identifies a feed-forward loop involving mTORC2/AKT/HSF1/HuR that regulates Rictor expression and promotes glioblastoma growth.

bioRxiv · May 19, 2017Cancer Biology