Disordered Proteins Enable Histone Chaperoning on the Nucleosome
P. O. Heidarsson, D. Mercadante, A. Sottini, D. Nettels, M. B. Borgia, A. Borgia, S. Kilic, B. Fierz, R. B. Best, B. Schuler
The paper shows that disordered regions in proteins like H1 enable competitive displacement by histone chaperones such as prothymosin on the nucleosome.
bioRxiv · Apr 17, 2020Biophysics