Author

A. Brun

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:variant calling· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

B. Borrego· 3 shared S. Moreno· 2 shared A. I. de Avila· 1 shared C. Alonso· 1 shared E. Domingo· 1 shared I. Mingarro· 1 shared L. Gadea-Salom· 1 shared L. Martinez-Gil· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersMicrobiology

B. Borrego

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The Rift Valley fever (RVF) vaccine candidate 40Fp8 shows an extreme attenuation in IFNARKO mice following intranasal inoculation

B. Borrego, C. Alonso, S. Moreno, N. de la Losa, P. J. Sanchez-Cordon, A. Brun

The paper evaluates the safety of the RVF vaccine candidate 40Fp8 in immunosuppressed mice, showing it is highly attenuated compared to other vaccine viruses.

bioRxiv · Feb 20, 2024Pathology

Identification of small molecules with virus growth enhancement properties

M. J. Garcia-Murria, L. Gadea-Salom, S. Moreno, O. Zaragoza, A. Brun, I. Mingarro, L. Martinez-Gil

This paper identifies small molecules that enhance virus growth by promoting host-virus membrane fusion, with ethynylestradiol shown to boost SARS-CoV-2 and Influenza A virus growth in vitro.

bioRxiv · Nov 8, 2022 · PreprintMicrobiology

A hyper-attenuated variant of Rift Valley fever virus (RVFV) generated by a mutagenic drug (favipiravir) unveils potential virulence markers

B. Borrego, A. Brun

The paper characterizes a favipiravir-resistant RVFV variant that is attenuated and immunogenic, identifying mutations in RdRp and NSs genes as potential virulence markers.

bioRxiv · Oct 16, 2020Microbiology

Lethal mutagenesis of Rift Valley fever virus induced by favipiravir

B. Borrego, A. I. de Avila, E. Domingo, A. Brun

This study shows favipiravir reduces Rift Valley fever virus infectivity in cell cultures and animal models by inducing lethal mutagenesis.

bioRxiv · May 11, 2019Microbiology