Author

L. Martinez-Gil

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

I. Mingarro· 4 shared M. J. Garcia-Murria· 3 shared G. Duart· 2 shared L. Gadea-Salom· 2 shared A. Brun· 1 shared A. Elazar· 1 shared B. Grau· 1 shared J. M. Acosta-Caceres· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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4 shared papersBiochemistry

I. Mingarro

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Author profile →

4 papers

Recent·Most cited

Computational design of BclxL inhibitors that target transmembrane domain interactions

G. Duart, A. Elazar, J. Weinstein, L. Gadea-Salom, J. Ortiz-Mateu, S. Fleishman, I. Mingarro, L. Martinez-Gil

This study develops a computational method to design inhibitors targeting transmembrane domain interactions of BclxL, demonstrating their ability to block anti-apoptotic effects.

bioRxiv · Nov 9, 2022Biochemistry

Identification of small molecules with virus growth enhancement properties

M. J. Garcia-Murria, L. Gadea-Salom, S. Moreno, O. Zaragoza, A. Brun, I. Mingarro, L. Martinez-Gil

This paper identifies small molecules that enhance virus growth by promoting host-virus membrane fusion, with ethynylestradiol shown to boost SARS-CoV-2 and Influenza A virus growth in vitro.

bioRxiv · Nov 8, 2022 · PreprintMicrobiology

SARS-CoV-2 envelope protein topology in eukaryotic membranes

G. Duart, M. J. Garcia-Murria, B. Grau, J. M. Acosta-Caceres, L. Martinez-Gil, I. Mingarro

The paper determines the topology of SARS-CoV-2 E protein in eukaryotic membranes, showing it is a single-spanning protein with N-terminus extracellular and C-terminus cytoplasmic.

bioRxiv · May 27, 2020Biochemistry

A Bimolecular Multicelular complementation system for the detection of syncytium formation: A new methodology for the identification of entry inhibitors

M. J. Garcia-Murria, N. Exposito-Dominguez, I. Mingarro, L. Martinez-Gil

This paper introduces a new method to detect syncytium formation and uses it to identify entry inhibitors for Nipah virus.

bioRxiv · Jan 17, 2019Microbiology