Goblet cell LRRC26 regulates BK channel activation and protects against colitis in mice
V. M. Gonzalez-Perez, P. L. Martinez-Espinosa, M. Sala-Rabanal, N. Bharadwaj, X. Xia, A. C. Chen, D. Alvarado, J. K. Gustafsson, H. Hu, M. A. Ciorba, C. J. Lingle
This study shows that LRRC26-associated BK channels in goblet cells protect mice from colitis by regulating potassium flux and MUC2 secretion.
bioRxiv · Oct 23, 2020Physiology