Author

D. Alvarado

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:development & morphogenesis· 1 Assay:electrophysiology· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

A. C. Chen· 1 shared A. Iavarone· 1 shared A. Lasorella· 1 shared A. Muller· 1 shared C. J. Lingle· 1 shared C. V. Rothlin· 1 shared E. J. Alberto· 1 shared F. X. Vazquez· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperPhysiology

A. C. Chen

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Author profile →

3 papers

Recent·Most cited

Molecular Dynamics Study of α-Synuclein Domain Deletion Mutant Monomers

N. Onishi, N. Mazzaferro, S. Kunstelj, D. Alvarado, A. Muller, F. X. Vazquez

This study uses molecular dynamics simulations to analyze how domain deletions in α-synuclein affect protein structure and interactions with lipid membranes.

bioRxiv · Mar 23, 2024 · PreprintBiophysics

Tissue-specific modifier alleles determine Mertk loss-of-function traits

Y. T. Akalu, M. E. Mercau, M. Ansems, S. Wagage, L. D. Hughes, J. Nevin, E. J. Alberto, X. E. Liu, L.-Z. He, D. Alvarado, T. Keler, Y. Kong, W. M. Philbrick, S. C. Finnemann, A. Iavarone, , S. Ghosh

This study shows that Mertk loss-of-function traits depend on tissue-specific modifier alleles, not just Mertk itself.

bioRxiv · May 23, 2022Immunology

Goblet cell LRRC26 regulates BK channel activation and protects against colitis in mice

V. M. Gonzalez-Perez, P. L. Martinez-Espinosa, M. Sala-Rabanal, N. Bharadwaj, X. Xia, A. C. Chen, D. Alvarado, J. K. Gustafsson, H. Hu, M. A. Ciorba, C. J. Lingle

This study shows that LRRC26-associated BK channels in goblet cells protect mice from colitis by regulating potassium flux and MUC2 secretion.

bioRxiv · Oct 23, 2020Physiology