Development of a polymicrobial checkerboard assay as a tool for determining combinatorial antibiotic effectiveness in polymicrobial communities
C. Black, H. Al Mahmud, S. Wilson, A. C. Smith, C. A. Wakeman
This paper develops a polymicrobial checkerboard assay to assess combinatorial antibiotic effectiveness in mixed bacterial communities, finding that visible turbidity is not reliable and polymicrobial interactions can reduce antibiotic efficacy.
bioRxiv · Oct 12, 2022Microbiology