Fast bacterial growth reduces antibiotic accumulation and efficacy
U. Łapinska, M. Voliotis, K. K. Lee, A. Campey, R. Stone, W. Phetsang, B. Zhang, K. Tsaneva-Atanasova, M. Blaskovich, S. Pagliara
The paper identifies fast-growing bacterial variants that avoid antibiotic accumulation and survive treatment without genetic mutations, challenging the current understanding of antibiotic resistance mechanisms.
bioRxiv · Oct 18, 2021Microbiology