Author

A. Cheruiyot

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1 Assay:Ribo-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

B. A. Wadugu· 1 shared B. Sullivan· 1 shared D. C. Link· 1 shared D. He· 1 shared D. S. Lemacon· 1 shared E. A. Obeng· 1 shared F. Xiao· 1 shared H. Pan· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

B. A. Wadugu

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Author profile →

2 papers

Recent·Most cited

Sustained hyperglycemia specifically targets translation of mRNAs for insulin secretion

A. Cheruiyot, J. Hollister-Lock, B. Sullivan, H. Pan, J. M. Dreyfuss, S. Bonner-Weir, J. E. Schaffer

This study shows that sustained high glucose reduces translation of mRNAs involved in insulin secretion in beta-cells, impairing their function.

bioRxiv · Sep 29, 2023Cell Biology

Nonsense Mediated RNA Decay Is a Unique Vulnerability of Cancer Cells with SF3B1 and U2AF1 Mutations

Z. You, A. Cheruiyot, S. Li, S. N. Srivatsan, T. Ahmed, Y. Chen, D. S. Lemacon, Y. Li, Z. Yang, B. A. Wadugu, W. Warner, S. M. Pruett-Miller, E. A. Obeng, D. C. Link, D. He, , M. J. Walter

This study identifies NMD as a vulnerability in cancer cells with SF3B1 and U2AF1 mutations, showing increased sensitivity to NMD inhibition and potential therapeutic targeting.

bioRxiv · Mar 19, 2021Cell Biology