Author

S. A. E. Young

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

A. Cipitria· 2 shared D. S. Garske· 2 shared A. Abaurrea· 1 shared A. Ellinghaus· 1 shared A. Grueneboom· 1 shared A. R. Varadarajan· 1 shared A. Riestra· 1 shared A.-D. Heller· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBioengineering

A. Cipitria

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Dormancy-inducing 3D-engineered matrix uncovers mechanosensitive and drug protective FHL2-p21 signaling axis

S. Bakhshandeh, U. Heras, H. M. Taieb, A. R. Varadarajan, S. M. Lissek, S. M. Huecker, X. Lu, D. S. Garske, S. A. E. Young, A. Abaurrea, M. M. Caffarel, A. Riestra, P. Bragado, J. Contzen, M. Gossen, , A. Cipitria

The paper identifies a mechanosensitive FHL2-p21 signaling axis in dormant cancer cells using 3D-engineered matrices, showing its role in drug resistance and potential as a target for therapy.

bioRxiv · Jan 25, 2023Bioengineering

From breast cancer cell homing to the onset of early bone metastasis: dynamic bone (re)modeling as a driver of metastasis

S. A. E. Young, A.-D. Heller, D. S. Garske, M. Rummler, V. Qian, A. Ellinghaus, G. N. Duda, B. Willie, A. Grueneboom, A. Cipitria

This study develops a mouse model and multimodal 3D imaging to analyze cancer cell homing and dynamic bone remodeling during early bone metastasis, revealing osteolytic lesions in specific bone regions.

bioRxiv · Jan 24, 2023 · PreprintBioengineering