Glycan shield of the ebolavirus envelope glycoprotein GP
W. Peng, V. Rayaprolu, A. D. Parvate, M. F. Pronker, S. Hui, D. Parekh, K. Shaffer, X. Yu, E. O. Saphire, J. Snijder
This study profiles the site-specific glycosylation patterns of ebolavirus GP using mass spectrometry, revealing complex N-, O-, and C-linked glycans that contribute to the glycan shield and restrict antibody neutralization.
bioRxiv · Feb 7, 2022Biochemistry