Cancer BiologybioRxivPreprint
P2RX7 inhibition reduces breast cancer induced osteolytic lesions - implications for bone metastasis
K. M. Shah, L. Tattersall, A. Hussain…·A. Gartland
This study shows that inhibiting P2RX7 reduces osteolytic lesions in a murine breast cancer model by increasing cancer cell death and decreasing osteoclast numbers.
DOI 10.1101/2021.12.31.474644