Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
14 papers
Recent·Most cited
E. E. Adjei-Sowah, I. Chandrasiri, B. Xiao, Y. Liu, J. Ackerman, C. Soto, A. E. Nichols, K. Nolan, D. S. W. Benoit, A. E. Loiselle
This paper develops a nanoparticle-based drug delivery system targeting tendons to improve healing by delivering Niclosamide, showing enhanced functional and mechanical outcomes compared to systemic delivery.
bioRxiv · Nov 29, 2023Bioengineering
J. E. Ackerman, E. Adjei-Sowah, A. Korcari, S. N. Muscat, A. E. Nichols, M. R. Buckley, A. E. Loiselle
The paper identifies Periostin as a critical niche supporting myofibroblast dynamics and fibrosis during tendon healing, suggesting it as a therapeutic target.
bioRxiv · Jul 21, 2023Cell Biology
A. E. Nichols, L. Benoodt, E. Adjei-Sowah, K. Jerreld, A. Kollar, C. Ketonis, A. E. Loiselle
bioRxiv · Jan 30, 2023 · PreprintCell Biology
K. E. Mora, S. J. Mlawer, A. E. Loiselle, M. R. Buckley
This study characterizes the micromechanical strain environment in impinged Achilles tendon insertion using a mouse model and finite element analysis, showing transverse compression and cell deformation.
bioRxiv · Sep 25, 2022 · PreprintBioengineering
S. Muscat, A. E. Nichols, E. Gira, A. E. Loiselle
This study examines the role of CCR2 in tendon healing by analyzing CCR2GFP/+ and knockout mice, finding that CCR2 deficiency reduces macrophages and impairs healing.
bioRxiv · Jul 20, 2022 · PreprintCell Biology
M. B. Geary, C. A. Orner, H. Shammas, J. M. Reuter, A. E. Loiselle, B. D. Giordano, C.-L. Wu
This study shows that abductor injury in mice leads to hip osteoarthritis, with cartilage degeneration and collagen loss, suggesting a link between muscle pathology and OA development.
bioRxiv · May 22, 2022 · PreprintPathology
A. Korcari, S. Muscat, M. Buckley, A. E. Loiselle
This study shows that depletion of Scleraxis-lineage cells during tendon healing impairs early structural and functional recovery but not long-term tendon mechanics.
bioRxiv · Mar 17, 2022 · PreprintCell Biology
A. Korcari, A. E. Nichols, A. E. Loiselle
This study shows that depletion of Scleraxis-lineage cells in mice accelerates tendon extracellular matrix aging, revealing distinct functional changes in aged versus DTR tenocytes.
bioRxiv · Jan 20, 2022Cell Biology
A. Korcari, A. E. Loiselle, M. R. Buckley
This study characterizes scar tissue biomechanics in adult murine flexor tendon healing and shows that testing composite tendons overestimates scar properties, highlighting the need for scar isolation methods.
bioRxiv · Nov 9, 2021Bioengineering
A. E. Nichols, S. N. Muscat, A. E. Loiselle
This study tests RAGE antagonism's effect on diabetic tendon healing and homeostasis, finding no improvement in healing but transient disruption in control tendons.
bioRxiv · May 11, 2021 · PreprintPathology
A. E. Nichols, S. E. Miller, L. J. Green, M. S. Richards, A. E. Loiselle
This study compares isolation methods for tendon cells in vitro, finding that explant methods reduce proliferative capacity and alter lineage composition compared to digestion methods.
bioRxiv · Mar 7, 2021Cell Biology
J. Kallenbach, M. Freeberg, D. Abplanalp, J. Lillis, J. Ashton, A. E. Loiselle, M. Buckley, A. van Wijnen, H. A. Awad
The study compares tendon healing in MRL/MpJ and C57Bl/6J mice, finding altered TGFB1 pathways in MRL mice that reduce fibrosis and promote faster healing.
bioRxiv · Feb 8, 2021Cell Biology
B. Qiu, J. Cobb, A. E. Loiselle, C. Ketonis
This paper develops a murine model of pyogenic flexor tenosynovitis using Staphylococcus aureus infection and evaluates its progression through bioluminescence and histopathology.
bioRxiv · Feb 7, 2020Pathology
K. T. Best, A. Korcari, K. E. Mora, E. Knapp, M. R. Buckley, A. E. Loiselle
This study depletes Scleraxis-lineage cells in adult tendons and finds improved biomechanical properties and altered collagen structure, suggesting a role in homeostasis rather than repair.
bioRxiv · Feb 1, 2020Cell Biology